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Modafinil: The cognitive enhancer


In this world of tough competition we can hardly afford to be left behind in our tracks. Failing to be on par with our counterparts can seriously hamper our health and also our path to success can be restricted. It is important that we should maintain the cognition of the mind at sharp levels at all times. However studies have shown that an average person can only maintain optimum focus at a stretch for 20 minutes. That is not enough time for someone to accomplish a task that requires high focus and attention. So how do we maintain the same level of focus for longer periods of time?
The answer to this question can be found with the concept of Nootropics.



Modafinil is perhaps the most commonly known smart drug compound in the world. It was FDA Approved in the year 1998 for sale and use for wakefulness and cognition enhancement purposes. In fact the benefits of the smart drug/ compound are such that Modafinil was nicknamed ‘The Smart Drug King’.

Let us look into how the medication works.

The Modafinil smart drug compound helps in the wakefulness and the cognitive enhancement of the smart drug user. Modafinil stimulates the Orexin receptors (OX1 and OX2). These receptors are also called Hypocretin receptors. Following the stimulation the Orexin (or Hypocretin) peptide is activated that helps in the wakefulness of a person. After the activation, the med now impacts on the Dopamine neurotransmitter of the body. Dopamine is an important neurotransmitter that helps in the wakefulness and the cognitive enhancement of the user. After one takes this drug, the reuptake of the Dopamine neurotransmitter in the body is inhibited that results in the formation of a pool of Dopamine in the body; or rather at the vicinity of the reuptake point. This accumulated Dopamine is later used by the body for its daily uses. Along with Dopamine other hormones that are responsible directly or indirectly for the wakefulness and the cognition of the user. Histamine (regulates the sleep cycle), Norepinephrine (promotes wakefulness and elevates the heart rate), Serotonin (regulates the mood, improves the memory and also aids in the process of the creation of new neurons [Neurogenesis]) are increased that helps in the wakefulness, cognitive enhancement and the development of the various executive brain functions.

Uses

  • Modafinil is a Eugeroic drug that helps in the promotion of wakefulness in the body. The increase of Dopamine, the activation of Orexin peptide and other hormones helps the person wake up.
  • The cognition and the executive brain functions like memory and focus are also increased.
  • Various sleeping disorders like Narcolepsy, sleep apnea are also treated with the use of this smart drug.
  • People suffering from Shift Work disorder are also helped with the use of this drug. A single pill of this drug can help the person go through the shift with utmost focus and motivation.
  • Since it also elevates the level of Serotonin the mood of the person is also elevated that helps in the treatment of depression and reduces fatigue to a great extent.

Modafinil users are known to have reported feeling euphoric owing to the mood elevating properties of the medication. As such they report experiencing a clear headed energy that helps them take proper decisions and also reap the full benefits of their mind while in the action period of this drug. Modafinil and its subsequent brand versions are known to last for 12-13 hours.

Side effects

  • Headache
  • Nausea
  • Upset stomach
  • Nervousness, anxiety
  • Muscular pain, etc.
  • In some rare cases allergic reactions are experienced by Modafinil users.

Who should avoid the smart drug Modafinil?

  • People with cardiac, renal and hepatic ailments
  • People with an allergy of Modafinil
  • People with a past history of drug abuse
  • Pregnant and breastfeeding women


Modafinil is however a strong drug and should be taken with care. Proper precautions help in the person reaping the full benefits of the smart drug. Precautions like avoiding the use of alcohol and the proper consultation with a medical professional can go a long way for Modafinil users. Do not abuse the drug, as it can have heavy medical implications. 



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